Top Ten (10) Strangest Diseases

Diseases that cause or limbs to become grossly large or lead us through an entire life cycle in just ten years may sound like fiction, however over a hundred million people suffer from the following ten strangest diseases.

Diseases that cause or limbs to become grossly large or lead us through an entire life cycle in just ten years may sound like fiction, however over a hundred million people suffer from the following ten strangest diseases.

10. Walking Corpse Syndrome: Characterized by people who believe they have died.

The syndrome has highly suicidal tendencies and depression, during which the sufferer complains of having lost everything including possessions and part of or their entire body. They believe that they have died and are walking as a corpse. The delusion is generally expanded to the degree that the patient might state that he can feel and smell his own rotting flesh as worms crawl through the skin.

9. Vampire Disease: Characterized by pain from the sun

Some people in this world must take extreme measure to avoid the sun. Exposure to the sun makes their skin blister. Many of these people have pain and blistering as soon as the skin is exposed to the sun. This vamper like symptom, gave the disease its name.

8. Jumping Frenchman Disorder: Characterized by strange reflexes

The primary characteristic of the disease is that it leaves patients highly startled by any unexpected sight or noise. Far more than twitching when someone sneaks up behind you, sufferers of this disorder cry out, flail their arms and repeat words. The disorder was first found in some of Maine's lumberjacks of French Canadian origin, the odd reflex has been identified throughout other parts of the world too.

7. Blaschko's Lines: Characterized by strange stripes all over the body

Blaschko's lines are very rare and an unexplained phenomenon of human anatomy discovered in 1901 by Alfred Blaschko, a German dermatologist. Blaschko's lines are an invisible pattern built into human DNA. Many acquired and inherited diseases of the skin or mucosa appear according to these patters. This creates the visual appearance of stripes on the human body.

6. Pica: Characterized by the urge to eat non-food substances

People suffering from Pica have an endless urge to eat various types of non-food substances including paper, dirt, glue and clay. Health experts have not found a real cause nor a cure for this disease despite reports that it may be linked to mineral deficiency.

5. Alice in Wonderland Syndrome: Characterized by time, space and body image distortion

Alice in Wonderland Syndrome (AIWS), or micropsia, is a highly disorienting neurological condition which affects human visual perception. Sufferers of the disease view humans, animals, parts of humans and inanimate objects as substantially smaller than in reality. Most often, the object perceived appears further away or extremely close all at the same time. For example, a normal sized car, may appear as a small toy and a pet dog may be perceived as being the size of a mouse.

4. Blue Skin Disorder: the blue people

Throughout the 1960s a large family of "blue people" resided in the Kentucky hills near Troublesome Creek. They were known as the Blue Fugates. Many never had a serious illness and most lived past aged 80 despite having blue skin. The trait was passed from generation to generation. Many people with this condition have blue, indigo, plum or almost purple skin.

3. Werewolf Syndrome: Characterized by excessive hair

Young children suffering from this disease can grow large, dark, hairy patches on their face. The disease is called Werewolf syndrome because people resemble werewolves with excessive hair and without the sharp teeth or claws.

2. Elephantiasis: Characterized by grossly enlarged members

Lymphatic filarisis which is also called elephantiasis, is best seen from dramatic photos of individuals with grossly enlarged or swollen legs and arms. The disease is caused by parasitic worms which are all transmitted by mosquitoes. The disease affects 120 million people throughout the world and 40 million of these people have serious disease. An infected female mosquito bites a person and injects larvae into the blood. The larvae spread and can live for many years. Ultimately the parasites accumulate in the surrounding tissues. The common signs of this disease are overlarged arms legs, breasts and genitalia.

1. Progeria: Characterized by children looking as though they are 90 years old.

Progeria is caused by one tiny defect within the child's genetic code. This disease has very hard and devastating consequences. Most children born with the disease will die by the age of 13. As their bodies speed through the process of aging, they develop physical symptoms of older people including heart disease, premature baldness, thinning bones and arthritis. This disease is extremely rare with only 48 people living with it throughout the world. There is one family however with five children suffering from the disease.


10 years 18 weeks ago, 5:56 AM



I need to know that all these diseases have a cure or not. till now is there any remedy to fight back?

10 years 18 weeks ago, 5:27 PM


Where to start...

Blue skin disease is not hereditary. It is caused by heavy metal poisoning.

The term "werewolf syndrome" is extremely offensive. Hirsuitism is the correct term.

You probably should check everything on this page, as most of your facts are wrong. Start by googling "mosaicism".

10 years 7 weeks ago, 6:04 AM



i am grateful did not get the progeria because i am the same age as them

9 years 44 weeks ago, 6:29 PM



this is amazing!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

9 years 44 weeks ago, 6:32 PM



l feel bad for them and hope they find a cure.

9 years 44 weeks ago, 6:50 PM


Ebear's picture

Speaker of the House
Join Date:
Jun 2008
elgin, il, United States
makes you wonder

reading the different articles and seeing the pictures makes me thankful for my health and that of my matter how bad my day has gone, theses people have it way worse.makes you think.

...check... G-AZ
9 years 43 weeks ago, 1:01 PM


blue skin

There are different causes for blue skin. It can be hereditary if it is caused by methemoglobinemia.

Werewolf syndrome is the common name, much like dwarf or midget for little people, it can be offensive, but it is the common name.

I can't see how mosaicism has to do with any of this. To second poster: You need to check YOUR facts next time.

9 years 42 weeks ago, 10:04 PM


silvergryfon's picture

Join Date:
Jun 2008

Is liberalism a disease? If so, it is really common, like the flu.

9 years 42 weeks ago, 10:07 PM


sarge225's picture

Join Date:
Apr 2008
Lafayette, Louisiana, United States

i think we could say theres an outbreak!

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